Supernormal scotopic ERG in cone dystrophy.

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Supernormal scotopic ERG in cone dystrophy.

Three patients with a bull's-eye macular lesion and other signs characteristic of cone dystrophy gave an unusual ERG finding. In response to a white flash of moderate intensity the scotopic b-wave amplitude was considerably larger than normal. One patient had elevated rod thresholds and nyctalopia, while the other 2 had normal rod sensitivity associated with the supernormal scotopic b-wave ampl...

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PIII and derived PII analysis in a patient with retinal dysfunction with supernormal scotopic ERG Subtitle: Retinal dysfunction with supernormal scotopic ERG

Purpose: To present electroretinographic (ERG) findings in a patient with retinal dysfunction with supernormal scotopic ERG, and to analyze rod and cone PIII components and rod inner nuclear layer (derived PII) responses. Patient: A Japanese 11-year-old girl complained of poor visual acuity. There was no parental consanguinity in her family. The corrected visual acuity was 0.7 in both eyes. No ...

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Novel KCNV2 mutations in cone dystrophy with supernormal rod electroretinogram.

PURPOSE To describe patients with cone dystrophy and supernormal rod electroretinogram (ERG) and search for mutations in the recently described KCNV2 gene. DESIGN Clinical and molecular study. METHODS Patients from three families originating from France, Morocco, and Algeria had standard ophthalmologic examination and color vision analysis, Goldmann perimetry, International Society for Clin...

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Visual Psychophysics and Physiological Optics Cone Dystrophy With ‘‘Supernormal’’ Rod ERG: Psychophysical Testing Shows Comparable Rod and Cone Temporal Sensitivity Losses With No Gain in Rod Function

Citation: Stockman A, Henning GB, Michaelides M, et al. Cone dystrophy with ‘‘supernormal’’ rod ERG: psychophysical testing shows comparable rod and cone temporal sensitivity losses with no gain in rod function. Invest Ophthalmol Vis Sci. 2014;55:832–840. DOI:10.1167/iovs. 13-12919 PURPOSE. We report a psychophysical investigation of 5 observers with the retinal disorder ‘‘cone dystrophy with s...

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Cone dystrophy with "supernormal" rod ERG: psychophysical testing shows comparable rod and cone temporal sensitivity losses with no gain in rod function.

PURPOSE We report a psychophysical investigation of 5 observers with the retinal disorder "cone dystrophy with supernormal rod ERG," caused by mutations in the gene KCNV2 that encodes a voltage-gated potassium channel found in rod and cone photoreceptors. We compared losses for rod- and for cone-mediated vision to further investigate the disorder and to assess whether the supernormal ERG is ass...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1984

ISSN: 0007-1161

DOI: 10.1136/bjo.68.2.69